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1.
Front Public Health ; 12: 1375238, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38500727

RESUMO

Introduction: UTA can provide older adult people with the satisfaction of needs and creates the opportunity to pursue youthful interests and passions. The aim of the study was to assess selected elements of the lifestyle of Silesian seniors, taking into account their participation in the activities of Universities of the Third Age. Methods: The study involved 631 (100%) senior residents of the Silesian agglomeration. The majority of the study group were women (475; 75.28%), and the average age of the participants was 70.28 ± 6.09 years. To conduct the study, an original survey questionnaire was used, complemented by PPS-10, PAQE and Yesavage Geriatric Depression Rating Scale. Results: Among the surveyed Silesian seniors who did not attend classes at the University of the Third Age, a statistically significantly higher score on the Yesavage's Geriatric Depression Rating Scale was found compared to those confirming their participation in the mentioned activity (p = 0.002). Almost 40% (107; 38.63%) of seniors who did not attend classes at the Universities of the Third Age showed a high level of stress, and every fourth (89; 25.14%) Silesian senior taking part in the above-mentioned activity had a low level of stress (p = 0.04). The median of points obtained on the physical activity assessment scale (PAQE) by seniors attending classes at Universities of the Third Age was statistically higher than seniors who denied participation in the mentioned activity (p = 0.017). Conclusion: Participation in the various activities at the Universities of the Third Age influenced positively well-being, reduced stress and raised physical activity of examined seniors. It is important to promote and start actions leading to seniors' better and easier inclusion to the society life. Future research should concentrate on reasons why many seniors do not attend activities in their leisure time - especially on accessibility of various activities and financial reasons, which in the future will play crucial role in the aging societies.


Assuntos
Envelhecimento , Estilo de Vida , Humanos , Masculino , Feminino , Idoso , Pessoa de Meia-Idade , Universidades , Inquéritos e Questionários , Exercício Físico
2.
Biomedicines ; 12(3)2024 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-38540214

RESUMO

The aim of the study was to assess the occurrence of classic risk factors in the study group of patients with heart failure and to link them with the transcriptional activity of the examined genes: metalloproteinase 9 (MMP-9) and the tissue inhibitor of metalloproteinases 1 (TIMP-1). A total of 150 (100%) patients qualified for the study, including 80 (53.33%) patients with heart failure in the course of coronary artery disease, 40 (26.67%) with coronary artery disease without heart failure, and 30 (20.00%) in whom the presence of atherosclerotic changes in the coronary arteries was excluded. The material for molecular tests was peripheral blood collected from patients within the first 24 h of hospitalisation. A quantitative analysis of transcriptional activity was performed using the RT-qPCR technique. The most common classic risk factors among the patients in the study group were arterial hypertension (117; 78.00%) and overweight/obesity (102; 68%). In the group of patients with coronary artery disease and heart failure burdened with overweight/obesity, a significantly higher transcriptional activity of the metalloproteinase 9 (MMP-9) gene was found in comparison to patients who were not burdened with this risk factor. The analysis also showed the statistically significant higher transcriptional activity of the metalloproteinase 9 (MMP-9) gene in a group of patients with coronary artery disease and heart failure who smoked. The examined patients with heart failure due to myocardial ischemia were burdened with numerous cardiovascular risk factors, the most common of which were arterial hypertension, obesity/overweight, and hypercholesterolemia. A significant increase in the transcriptional activity of the metalloproteinase 9 (MMP-9) gene in the presence of risk factors (male sex, overweight/obesity, smoking) indicates another pathomechanism of their action and participation in the development and progression of heart failure during myocardial ischemia. There is a need for systematic information and educational activities promoting a healthy lifestyle with the elimination of modifiable risk factors for cardiovascular diseases.

3.
Biomedicines ; 11(10)2023 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-37893149

RESUMO

The most common cause of heart failure (HF) is coronary artery disease (CAD). The aim of this study was to evaluate the transcriptional activity of the metalloproteinase 9 (MMP-9) and tissue metalloproteinase inhibitor 1 (TIMP-1) genes in a study group of patients with HF due to CAD and in the control group, as well as assess the transcriptional activity of the examined genes, taking into account the number of affected coronary arteries and the severity of heart failure. The study group consisted of a total of 150 (100%) patients. The material for the study was peripheral blood, and molecular tests were performed using the quantitative QRT-PCR technique. The transcriptional activity of the MMP-9 gene was significantly higher in the group of patients with CAD and HF. It was also significantly higher with the progression of heart failure. TIMP-1 gene transcriptional activity was significantly lower with the advancement of heart failure. The transcriptional activity of the MMP-9 and TIMP-1 genes differentiated the examined patients. The severity of HF, and a significant increase in the QRT-PCR transcriptional activity of the MMP-9 gene with a simultaneous decrease in the activity of the TIMP-1 gene, makes them useful diagnostic and prognostic markers in clinical practice.

4.
Minerva Pediatr (Torino) ; 75(5): 650-659, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31833347

RESUMO

BACKGROUND: Movement and physical activity are the natural needs of a living human. Sedentary lifestyle resulting from the development of car communication, improper nutrition, abuse of drugs and addictive substances, constant rush and stress consequently cause destructive health effects. The aim of the study was to analyze risky behaviors among adolescents in the Silesian voivodeship (Poland), taking into account their resistance to stress and physical activity. METHODS: Two hundred eleven people were examined (100%). Among them there were 122 girls (57.82%) and 89 boys (42.18%) aged 16 to 18 years (x=17.3, SD=0.53). The participants were students from upper secondary schools in the Silesian voivodeship. The research tool was an original questionnaire consisting of a metric part, closed questions related to the examined problem and a standardized questionnaire of physical activity (Subjective Experience of Work Load [SEWL]). RESULTS: Most of the girls (47, 38.52%) considered themselves to be medically resistant to stress, while boys (30, 33.71%) believed they were rather resistant to stress. On the other hand, there was no correlation between susceptibility to stress of adolescents in relation to age. From the whole group, up to 203 people (96.21%) have already drunk alcohol. Among them there were 117 girls (95.90%) and 86 boys (96.63%). The first cigarette from the studied group of teenagers was ignited by 137 people (64.93%), including 80 girls (65.57%) and 57 boys (64.04%), while psychoactive substances have been already taken by 51 participants (24.17%). Among them there were 23 girls (18.85%) and 28 boys (31.46%). There was no correlation between the self-esteem of susceptibility to stress and the use of stimulants in both boys and girls. The average value of the Sport Index among girls was 2.75, while among boys was 6.37. CONCLUSIONS: Boys in comparison to girls considered themselves more resistant to stress, while the age in both sexes did not affect self-assessment of vulnerability to stress. Gender of the adolescents did not affect the frequency of stimulants use.


Assuntos
Exercício Físico , Esportes , Masculino , Feminino , Humanos , Adolescente , Estudantes , Inquéritos e Questionários , Comportamento Sexual
5.
BMC Public Health ; 22(1): 2342, 2022 12 14.
Artigo em Inglês | MEDLINE | ID: mdl-36517763

RESUMO

BACKGROUND: Protective vaccinations are one of the basic means of infectious disease prevention. The aim of the study was to assess the implementation of compulsory and additional protective vaccinations among adult Poles, their knowledge about the purpose of introducing a vaccination schedule and adverse events following immunization. Opinions about and support for anti-vaccination movements were also examined. MATERIALS AND METHODS: A total of 700 (100%) people aged 18 to 80 (x̅ = 32,16 ± 16,46) took part in the study, conducted using the proprietary questionnaire. All the participants selected randomly from patients of the Department of Cardiology, their visitors, doctors, nurses, paramedics, medical students, and authors' acquaintances gave their informed consent to participate in the study. RESULTS: About 10% of the respondents did not complete the compulsory vaccination schedule. Almost 80% of respondents believed that the main reason for vaccinations schedule occurrence was the desire to completely exclude certain diseases and their complications from the population. More than half of the respondents have never had any additional vaccination. A statistically significant correlation was found between intake of at least one additional vaccination and age (χ2=22.262, p = 0.002) and education level (χ2= 11.074, p = 0.004). Among the respondents, there was a group that classified autism as one of the adverse events following immunization. About 95% of respondents never experienced any adverse events following immunizationand as many as 30 respondents declared their support for anti-vaccination movements. CONCLUSION: The degree of the implementation of compulsory protective vaccinations in the study group was high, while additional vaccinations were insufficient. The purposefulness of introducing a vaccination schedule was correctly identified by the majority of the respondents, but the knowledge about adverse events following immunisation and their types was incomplete. Among participants were individuals who declared their support for anti-vaccination movements, so society should be constantly educated about vaccinations benefits.


Assuntos
Doenças Transmissíveis , Vacinação , Adulto , Humanos , Esquemas de Imunização , Imunização , Inquéritos e Questionários , Conhecimentos, Atitudes e Prática em Saúde
6.
BMC Public Health ; 22(1): 1949, 2022 10 20.
Artigo em Inglês | MEDLINE | ID: mdl-36266647

RESUMO

OBJECTIVES: Protective vaccinations are important in maintaining health and reducing suffering from infectious diseases. Also, vaccine-preventable infectious diseases are associated with the development and progression of cardiovascular diseases. AIM: The study aimed to test adults' knowledge of the role of protective vaccinations in the prevention of cardiovascular diseases, and their opinions on the quantity of the information provided by doctors in this regard. METHODS: A total of 700 adults participated in the study, most of whom were women (500; 71.43%). The study used an original questionnaire containing questions covering vaccinations and cardiovascular diseases, and the general characteristics of the participants. The inclusion criteria for the study were 18 years of age and written informed consent to participate in the study. RESULTS: Over 60% of the participants did not know of, or denied the possibility of, developing cardiovascular diseases as a result of avoiding required preventive vaccinations. More than half of the participants stated that there is no need to recommend influenza vaccination to patients with cardiovascular diseases. Over 70% of participants stated that family doctors did not provide sufficient information about protective vaccinations. CONCLUSION: In these adults, knowledge of the role of preventive vaccinations in the prevention of cardiovascular diseases was low, and the quantity of the information provided by doctors about preventive vaccinations were considered to be insufficient. Public awareness of the effects of avoiding preventive vaccinations should be raised especially among people with CVD.


Assuntos
Doenças Cardiovasculares , Doenças Transmissíveis , Vacinas , Adulto , Humanos , Feminino , Masculino , Doenças Cardiovasculares/prevenção & controle , Conhecimentos, Atitudes e Prática em Saúde , Vacinação
8.
Artigo em Inglês | MEDLINE | ID: mdl-35742539

RESUMO

Cardiovascular diseases are the most common causes of death, in both Poland and the world. Their development and progression are largely influenced by the lifestyle with the presence/occurrence of classic, modifiable risk factors. Among them, low physical activity plays a significant role. The aim of the study was to evaluate the expression of the endothelin-1 gene and its type A receptor, taking into account physical activity (International Physical Activity Questionnaire-IPAQ) among patients with acute myocardial infarction. A total of 234 patients with acute myocardial infarction were examined, including 167 patients undergoing early post-hospital cardiac rehabilitation and 67 not participating in it. All of them were assessed with the IPAQ questionnaire and the quantitative real-time polymerase reaction method (QRT-PCR). Physical activity in the group of patients after early post-hospital cardiac rehabilitation increased after rehabilitation. Transcriptional activity of the endothelin-1 (ET-1) gene in both studied group of patients increased significantly, but in a group of patients not participating in early post-hospital cardiac rehabilitation more than in a group of patients participating in it. In our study, the expression of ET-1 was also significantly higher in the group of patients with acute myocardial infarction with ST-segment elevation, without diabetes, with lipid disorders, smoking, with normal body weight. Expression of the ENDRA (Endothelin receptor A) gene increased with age. These results prove the beneficial effect of rehabilitation and may indicate another pathomechanism of pro-atherogenic activity of above-mentioned factors.


Assuntos
Reabilitação Cardíaca , Infarto do Miocárdio , Reabilitação Cardíaca/métodos , Endotelina-1/genética , Exercício Físico , Humanos , Infarto do Miocárdio/genética , Infarto do Miocárdio/reabilitação , Fatores de Tempo
9.
Artigo em Inglês | MEDLINE | ID: mdl-35681946

RESUMO

"Coronary prone behaviour pattern" refers to a way of coping with environmental stressors, otherwise known as type A behaviour patterns. Stress, unlimited working hours, and the shift system are conducive to an "unhealthy life style", conducted by nurses. The aim of the study was to assess the "coronary prone behaviour pattern", taking into account health behaviour and work performed by Polish nurses. Method: This was a descriptive study conducted from June 2017 to May 2018 among nurses (N = 1080) working primary care or in training facilities in Silesia, Poland. Data were acquired through a series of questionnaires and are presented as descriptive statistics. Results: The "coronary prone behaviour pattern" (type A behaviour) was manifested by 333 (30.8%) nurses, type B by 272 (25.2%). The "coronary prone behaviour pattern" respondents showed a risk of developing a problem with alcohol (p = 0.003) less frequently compared with other respondents. In addition, nurses with the abovementioned behaviour pattern ate better (M = 16.66; SD = 6.11) compared with those with the type B behaviour pattern (M = 15.49; SD = 6.52). In terms of mental and physical wellbeing, people with type A behavioural patterns had significantly (p < 0.001) better mental and physical wellbeing and, on average, better results in coping with stress compared with other behavioural patterns of nurses. Conclusion: The occurrence of the "coronary prone behaviour pattern" was associated with the health-promoting behaviours of nurses being the subject of the analysis, i.e., better mental and physical wellbeing, better ability to cope with stress, and a lower risk of problems with alcohol and proper nutrition.


Assuntos
Enfermeiras e Enfermeiros , Personalidade Tipo A , Comportamentos Relacionados com a Saúde , Humanos , Estilo de Vida , Polônia , Inquéritos e Questionários
10.
Artigo em Inglês | MEDLINE | ID: mdl-35162668

RESUMO

The aim of the study was to determine the personality traits, strategies of coping with stress and psychophysical wellbeing of surgical and non-surgical Polish doctors. The study used the following questionnaires and scales: the Resiliency Assessment Scale, the Type D Personality Scale, the Framingham Type A Scale, the Mini COPE-Coping Inventory and the Wellbeing Scale. Doctors performing surgical specialties were characterized by a significantly higher level of resilience components, a more frequent occurrence of the type B behaviour pattern and less frequent type D personality than doctors performing non-surgical specializations. The Mini COPE point values were comparable between surgical and non-surgical physicians. The sense of psychological wellbeing was higher in surgical specialists. The higher the values of the Optimistic approach to life and the ability to mobilize oneself in difficult situations, the lower the values of the Turning to religion domain and the higher the values of the Denial domain correlated with the performance of surgical specialization. Men performing surgical specializations were more often optimistic and inclined to consume alcohol, while women with non-surgical specialization more often coped with stress by turning to religion. We conclude that the personality traits of Polish doctors vary depending on their specialization. Physicians' coping strategies do not differ depending on their specialization. The sense of mental wellbeing is higher in surgical specialists compared to non-surgical specialists. An optimistic approach to life and the ability to mobilize oneself in difficult situations, as well as coping with stress by denial are associated with the surgical specialization. Men performing surgical specialties more often declare optimism and a tendency to cope with stress by consuming alcohol or psychoactive substances, while women who perform non-surgical specializations more often cope with stress by turning to religion. Psychological screening tests and appropriate training, taking into account medical specialization, could be one way of improving resilience and coping with stress among doctors.


Assuntos
Adaptação Psicológica , Médicos , Feminino , Humanos , Masculino , Personalidade , Médicos/psicologia , Polônia , Estresse Psicológico/psicologia , Inquéritos e Questionários
11.
J Clin Med ; 10(18)2021 Sep 21.
Artigo em Inglês | MEDLINE | ID: mdl-34575386

RESUMO

The objective of the present study was to determine the effectiveness of a three-week Whole-Body Vibration (WBV) training on the vascular blood flow of the lower limbs in children with myelomeningocele. The secondary goal was to evaluate the effect of WBV on the ROM of lower limb joints in this population. A total of 30 children with MMC (7-16 years old) were enrolled in the study. Children were randomly allocated to two groups of equal numbers, using an envelope code. The experimental group underwent a 3-week WBV training, while the control group received a 3-week conventional physiotherapy (PT) program. The examination consisted of two parts: (1) Doppler USG examination of the lower limb vascular blood flow; (2) evaluation of ROM. The results obtained revealed three main findings. First, WBV training effectively improved blood flow by increasing flow velocities in all tested arteries, while the impact of the PT program was limited to a single parameter. Second, WBV training effectively improved vascular resistance in arteries of the lower legs, while the PT program did not achieve any significant differences. Third, both types of treatment intervention significantly improved ROM in all joints of the lower limbs in MMC participants.

12.
Wiad Lek ; 74(8): 2004-2010, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34537757

RESUMO

Both architecture and medicine have accompanied man for centuries. Both architects and doctors make every effort to ensure that the objects of their interest (buildings and the human body) comply with the Vitruvian principles of ideal construction. Doctors take steps to restore these principles in the event of a disease, and like architects, they try to keep the subject of their activities as long as possible. It can be said that this two professions have a common ancestor: the first physician known by name in general history - Imhotep - was not only an outstanding doctor, but also an architect. He designed and built the funerary complex in Saqqara on the basis of a combination of different types of burials from lower and upper Egypt. He also was the author of the prototype of the Edwin Smith Papyrus, discovered in Luxor, a document containing the rational and scientific approach of ancient physicians to diseases for which science dominates over magic. Historians are debating whether it is Imhotep, and not Hippocrates, who should be called the father of medicine. The 21st century forces both doctors and architects to take up newer and newer challenges and change standards. Both of these professions today are based on the service provider-recipient relationship. According to modern technologies, they both work in accordance with the guidelines displayed on the computer screen. Doctors take responsibility for human health and life, while architects - for interpersonal relationships created in the buildings they have designed.


Assuntos
Médicos , Atenção à Saúde , História Antiga , Humanos , Masculino
13.
BMC Public Health ; 21(1): 1392, 2021 07 13.
Artigo em Inglês | MEDLINE | ID: mdl-34256706

RESUMO

BACKGROUND: The vaccine is a preparation of biological origin containing antigens that stimulate the body's immune system to produce acquired immunity. Vaccines can contain killed or "live" (attenuated) microorganisms as well as fragments of these (antigens). Although many vaccines are used routinely in pregnancy to provide a seroprotective immune response for mother, fetus and neonate there is much controversy over their use during this unique time. The aim of the study was to find out about the knowledge of adult Poles on the use of preventive vaccinations during pregnancy. METHODS: The study involved 700 people (100%) aged 18 to 80 years ([Formula: see text] = 32.16 ± 16.46). Most of the respondents were women (511; 73%). The study consisted of 9 questions about preventive vaccinations of pregnant women and 5 questions about members of the studied group. The aforementioned questions formed the basis of the preparation of the presented article. RESULTS: A significant part of respondents (322; 46%) did not have knowledge on the topic of safeness of using preventive vaccinations during pregnancy, 196 (28%) respondents believed that such procedure is not safe. Most of the respondents (371; 53%) did not know about the possibility of using "live" vaccines during pregnancy. 14 (2%) of respondents believed that pregnancy should be terminated in case of administration of a "live" vaccine to a pregnant woman. According to 294 (42%) respondents, vaccinations with "live" vaccines should be completed at least 3 months before the planned pregnancy. The subjects were not aware of the issue of post-exposure vaccination against tetanus and rabies among pregnant women. The respondents' responses were divided on the issue of the safest trimester of pregnancy for vaccine administration. Almost 1/3 of the respondents (203; 29%) indicated the third trimester as the safest for their performance. CONCLUSION: The knowledge of the surveyed group, the majority of whom were women, about the use of vaccinations before and during pregnancy was unsatisfactory. There is a need to educate the public about the benefits and risks of performing or avoiding preventive vaccinations during pregnancy.


Assuntos
Complicações Infecciosas na Gravidez , Vacinação , Adulto , Feminino , Humanos , Imunização , Recém-Nascido , Masculino , Gravidez , Gestantes , Vacinas Atenuadas
14.
Healthcare (Basel) ; 9(7)2021 Jun 22.
Artigo em Inglês | MEDLINE | ID: mdl-34206617

RESUMO

BACKGROUND: Chronic stress, unlimited working time and the shift working system as well as sleep deficiency may lead to the occurrence of nutrition disorders among nurses. AIM: The aim of the paper was an assessment of the nutrition habits of nurses. It was an observational study conducted from June 2017 to May 2018 among nurses (n = 1080) in Silesia in Poland. Data was obtained using a range of questionnaires. RESULTS: Body mass index (BMI) of the analysed nurses demonstrated overweight/obesity in 490 (45.5%) of them. Nearly all the diets of the analysed nurses (n = 1021; 94.5%) required improvement. Younger nurses (<31 years old) demonstrated a greater tendency to indulge in habitual overeating, and those having additional employment demonstrated poorer nutrition habits compared to those without additional employment. CONCLUSION: The analysed nurses made numerous dietary mistakes which, as a consequence, can lead to obesity. Emotional overeating was the dominant nutrition habit in the studied group of nurses. Nurses who were overweight/obese, nurses who had additional employment and younger nurses demonstrated tendencies toward improper nutrition choices, i.e., the tendency to overeat or restrain oneself from eating.

15.
Artigo em Inglês | MEDLINE | ID: mdl-34152112

RESUMO

INTRODUCTION: Back pain diseases are among frequently reported health problems. Unfortunately, more often this problem also affects young people, high school students. Lifestyle that people are representing nowadays has a negative impact on their spine. Development of technology and transportation eliminates daily basic physical activity such as taking a walk to the school. Prolonged and inappropriate sitting posture during classes and using the computer at home are predisposing factors for back pain occurrence. PURPOSE: The aim of this paper was to analyze the frequency of back pain occurrence among high school youth and attempt to relate their occurrence frequency with sex, time spent in sitting position, anthropometric parameters and physical activity of examined students. MATERIAL AND METHODS: The examined group initially counted 272 teenagers, but ultimately 218 were taken into account for the analysis and 54 questionnaires were filled in incorrectly and rejected. All of them were high school students. Customized survey consisting of general part and closed questions regarding physical activity (Subjective Experience of Work Load - SEWL) was used as an examination tool. RESULTS: Examined youth spent on average 10.04 hours daily in a sitting position. As much as 195 (89.45%) of examined teenagers declared to experience back pain at least once in their lives. The most of teenagers (117; 53.67%) indicated lumbar spine pain. Girls more often felt spine pain issues in comparison to boys. Short stature of teenagers was often related to back pain occurrence. No correlation between time spent in sitting position and frequency of skeleton axis pain occurrence was noted. Among group of boys a relation between more frequent physical activity and less often spine pain occurrence was observed. CONCLUSIONS: 1. Spine pain is an important health problem of examined youth, occurring more frequent among girls than boys. 2. Body height correlate negatively with frequency of spine pain occurrence among youth. 3. Despite spending more than 10 hours daily in sitting position by examined youth, it didn't affect the frequency of back pain issues occurrence. 4. Higher physical activity of examined boys was related to less often back pains.

16.
Artigo em Inglês | MEDLINE | ID: mdl-33673276

RESUMO

Background: Nursing is a profession where staff are exposed to chronic stress. Mental resilience plays a significant role in the process of coping with these challenges. The aim of this study was to assess nurses' mental and physical wellbeing, as well as resilience, by taking into account the occurrence of risky behaviour among nurses in Poland. Methods: A descriptive study was carried out between June 2017 and May 2018 among nurses (n = 1080) employed in primary healthcare or in training centres in Silesia, Poland. Data were obtained from a number of questionnaires. Results: Over half of the nurses (n = 735; 68%) had an average psychophysical mood level resulting from stress, and 179 (16.6%) nurses had a low psychophysical mood. Those with a lower psychophysical mood showed a greater tendency towards developing improper eating habits (r = -0.23; p < 0.001). Most nurses had an average (n = 649; 60.1%) or low (n = 255; 23.6%) level of resilience. Higher resilience levels were observed in nurses aged over 30 years (p = 0.004) and in those with additional employment (p = 0.008). High resilience was associated with a lower intensity of risky behaviour. Conclusion: Most nurses in Poland display average and low levels of resilience, which can have unfavourable consequences for their health.


Assuntos
Enfermeiras e Enfermeiros , Resiliência Psicológica , Adaptação Psicológica , Idoso , Humanos , Saúde Mental , Polônia , Inquéritos e Questionários
17.
Minerva Cardiol Angiol ; 69(2): 172-177, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-32643898

RESUMO

BACKGROUND: Heart failure (HF) is a major cause of mortality in developed countries. Its formation is associated with a change in the transcriptional activity of many genes. The aim of the study was to select, from the group of genes related to coronary atherosclerosis and heart failure, genes differentiating patients with coronary heart disease and heart failure on the basis of myocardial ischemia from healthy people, and then genes differentiating patients with various stages of heart failure. METHODS: The study was carried out using the oligonucleotide microarray technique HG-U133A (Affymetrix, Santa Clara, CA, USA). Cluster analysis showed a homogeneous division of the study group into patients with heart failure and healthy patients with excluded coronary artery disease and patients with heart failure depending on the size of the left ventricle ejection fraction. RESULTS: The study showed that genes differentiating the group of patients from healthy people were: TGF-ß1, TIMP-1 and MMP-9. The analysis also showed that genes differentiated patients with advanced heart failure in the course of coronary disease and left ventricular ejection fraction (LVEF) 20% and patients from the group with 40% LVEF were MMP-9 and TIMP-1. CONCLUSIONS: Extracting from the group of genes related to coronary atherosclerosis and cardiac failure: MMP-9, TGF-ß1 and TIMP-1 differentiating patients with heart failure on the basis of myocardial ischemia in varying degrees of severity from healthy people may indicate their significant contribution to disease development. Also increased expression of the metalloproteinase gene 9 (MMP-9) with a simultaneous decrease in the expression of its tissue inhibitor 1 (TIMP-1) in the studied group of patients with ischemic heart failure differing in left ventricular ejection fraction LVEF makes them the markers of progression in failure.


Assuntos
Insuficiência Cardíaca , Metaloproteinase 2 da Matriz , Metaloproteinase 9 da Matriz , Inibidor Tecidual de Metaloproteinase-1 , Insuficiência Cardíaca/diagnóstico , Humanos , Metaloproteinase 9 da Matriz/metabolismo , Volume Sistólico , Inibidor Tecidual de Metaloproteinase-1/metabolismo , Função Ventricular Esquerda
18.
Medicina (Kaunas) ; 56(9)2020 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-32933100

RESUMO

Background and objectives: Recommendations for the control of stable patients with coronary artery disease (CAD) related to an adequate level of physical activity (PA). Practical experience shows that the PA level in most people with CAD is definitely too low in relation to the guidelines. The cause may be psychological factors and among them the fear of movement-kinesiophobia. The aim of this project was to examine the evaluation of psychometric features of the Polish version of the Tampa Scale for Kinesiophobia Heart (TSK Heart), used in people with CAD. Materials and methods: The study involved 287 patients with stable CAD: 112 women and 175 men. Age: 63.50 (SD = 11.49) years. Kinesiophobia was assessed using TSK Heart, physical activity (PA)-using the International Physical Activity Questionnaire (IPAQ), and anxiety and depression was examined using the Hospital Anxiety and Depression Scale (HADS). The structure of TSK was examined using principal component analysis (PCA), internal cohesion (Cronbach's alpha, AC), and content validity was calculated by linear regression. Results: PCA showed a three-factor TSK structure. One-dimensionality and satisfactory reliability were found: TSK Heart: AC = 0.878. Kinesiophobia as a predictor of PA: R2 = 0.162 (p = 0.000000). Anxiety and depression-TSK: R2 = 0.093 (p = 0.00000). Conclusions: The Polish version of TSK Heart for cardiac patients is characterized by good psychometric features. The use of it can improve the cooperation of rehabilitation teams for patients with CAD.


Assuntos
Doença da Artéria Coronariana , Transtornos Fóbicos , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Polônia , Psicometria , Reprodutibilidade dos Testes , Inquéritos e Questionários
19.
J Nurs Manag ; 28(7): 1725-1739, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32772471

RESUMO

AIM: To evaluate the factors affecting the health-related behaviours among nurses in Poland, including the influence of Type D personality. BACKGROUND: Some nurses appear to adopt an unhealthy lifestyle to cope with the stressful nature of their work, which can affect their professional performance and contribute to the burden on our health care system. However, the factors driving the health-related behaviours among nurses in Poland have not been adequately studied. METHOD: This was a descriptive study conducted from June 2017 to May 2018 among nurses (N = 1,080) working primary care or in training facilities in Silesia, Poland. Data were acquired through a series of questionnaires and are presented as descriptive statistics. RESULTS: A total of 379 (35%) nurses consumed alcohol in a harmful way, and ~20% were smokers. Almost all nurses (94.5%) could make dietary improvements. Over half (68%) reported moderate stress levels, and 179 (16.6%) were extremely stressed. Compared with non-Type D individuals, nurses with Type D personality more commonly used ineffective techniques for dealing with stress (i.e. denial and abreaction; p <.001), had lower mood (p <.001) and had a poorer diet (p = .001). CONCLUSION: The majority of nurses in Poland lead an unhealthy lifestyle and report moderate to severe levels of stress. Nurses with Type D personality more commonly use ineffective techniques for dealing with stress (i.e. avoidance strategies), have lower mood and have a poorer diet than those with non-Type D personality. IMPLICATIONS FOR NURSING MANAGEMENT: Promoting healthy behaviours and developing stress management techniques among nurses, particularly those with Type D personality, may improve nurses' well-being and professional performance, and help set a better example for patients.


Assuntos
Enfermeiras e Enfermeiros , Personalidade Tipo D , Adaptação Psicológica , Comportamentos Relacionados com a Saúde , Humanos , Polônia , Inquéritos e Questionários
20.
Ann Agric Environ Med ; 27(1): 56-60, 2020 Mar 17.
Artigo em Inglês | MEDLINE | ID: mdl-32208580

RESUMO

INTRODUCTION: The importance of the problem of reduced motor activity in the prophylaxis and treatment of many diseases has resulted in numerous adaptations of a diagnostic tool, both for the disease and for linguistic and cultural versions. This also applies to cardiovascular diseases. The significance of the problem, and encouraging results of several studies, have led to a wider use of this tool. This also applies to people suffering cardiologically in Poland, where this problem is poorly understood. This was the inspiration to undertake research on the explanation of the reasons for the limitation in the activation of cardiac patients. OBJECTIVE: The aim of the study was to determine the level of kinesiophobia in patients with CAD, and to assess its possible association with physical activity (PA), socio-demographic determinants and morbidity. MATERIAL AND METHODS: The study was cross-sectional and included 217 hospitalized patients with CAD: 94 women and 123 men; aged 67.39 years. PA was assessed using the short version of IPAQ, and kinesiophobia was assessed using TSK Heart in Polish adaptation. TSK HeartIPAQ correlations were found. RESULTS: More than 70% of the patients revealed high levels of kinesiophobia (TSK>37 points). There were no TSK associations with gender, BMI, socio-demographic variables, other conditions and duration of cardiovascular disease. The disease is the main cause of kinesiophobia and regardless of its nature, negatively affects the level of PA. CONCLUSIONS: The quality of life of patients with CAD at various stages and the effectiveness of cardiolog-ical rehabilitation are conditioned by PA.


Assuntos
Doença da Artéria Coronariana/psicologia , Movimento , Transtornos Fóbicos/psicologia , Idoso , Estudos Transversais , Exercício Físico , Medo , Feminino , Humanos , Masculino , Polônia , Qualidade de Vida/psicologia , Inquéritos e Questionários
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